Feb 15, 2021 · The results of a patient’s direct antiglobulin (DAT) / Coombs test are shown above. An eluate was performed, which reacted with 11 of 11 control RBCs tested by indirect …

Nov 28, 2023 · The pediatric hematologist is concerned about autoimmune hemolytic anemia and orders a direct antiglobulin test (DAT), which is negative and requests a peripheral blood …

Jul 19, 2021 · Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired autosomal clonal mutation of hematopoietic stem cells (HSCs) characterized by erythrocytic membrane defect

Oct 19, 2023 · Answer B is incorrect because the direct antiglobulin (Coombs) test is a nonspecific test. Both positive and negative results can be seen in a wide variety of disease …

Feb 26, 2025 · Performing a direct Coombs test may help detect the presence of autoantibodies For cases involving cold autoantibodies or cold reactive alloantibodies, incubating the red cells …

Aug 8, 2023 · Transfusion medicine - Adsorption (or adsorption studies) is an advanced serologic testing method used to separate warm autoantibodies from serum in order to appropriately …

Jun 25, 2021 · DAT: direct antiglobulin test AHTR: acute hemolytic transfusion reaction CBC: complete blood count LDH: lactate dehydrogenase PT: prothrombin time APTT: activated …

Jul 20, 2020 · The patient's direct antiglobulin test is 3+ positive for IgG and negative for C3d. The elution demonstrates the presence of anti-C and anti-Fya. The patient's phenotype, using a …

Oct 15, 2024 · Warm autoantibody is an antibody that binds to the patient's own red blood cells (RBCs) and reacts optimally at 37 °C (body temperature) Identified in routine blood bank …

May 11, 2021 · Interference is defined as a cause of clinically significant difference in the assay result, due to another component or property of the sample Most interferences are missed by …