Ligation is the joining of two nucleotides, or two nucleic acid fragments, into a single polymeric chain through the action of an enzyme known as a ligase.

Ligation is one of the crucial steps in gene cloning because the DNA ligase enzyme joins a DNA vector with the target gene sequence through their blunt or sticky ends.

Share Kids Definition ligation noun li· ga· tion lī-ˈgā-shən : the act of tying a bodily part (as a blood vessel) with a ligature

2 days ago · Explore the chemistry of DNA ligation, the catalytic engine (ligase), and how this fundamental process underpins modern biotechnology.

Cells naturally carry out ligation during DNA replication, when the Okazaki fragments are joined together. Cells also use ligation to repair DNA that has been damaged, either by normal cell …

Definition of ligation noun in Oxford Advanced Learner's Dictionary. Meaning, pronunciation, picture, example sentences, grammar, usage notes, synonyms and more.

LIGATION definition: 1. the act of tying a blood vessel or other tube in the body with a piece of thread or wire: 2…. Learn more.

Ligation of DNA is a critical step in many modern molecular biology workflows. The sealing of nicks between adjacent residues of a single-strand break on a double-strand substrate and the …

DNA ligase is a type of enzyme that facilitates the joining of DNA strands together by catalyzing the formation of a phosphodiester bond. It plays a role in repairing single-strand breaks in …

Aug 25, 2025 · Ligation refers to the fundamental process of binding, tying, or joining distinct components together. This concept applies across various scientific and medical disciplines. It …